E.U. May ‘Unravel’ if U.K. Quits, Official Says

LONDON — Almost 40 years after Britain joined the forerunner of today’s European Union, the debate over the country’s future in the Union has quickened with a warning from a top E.U. official that any moves to renegotiate the terms of British membership could wreck the bloc.

Herman Van Rompuy, president of the European Council, the body that groups the 27 E.U. member states, said that the European Union had benefited tremendously from British membership and that Britain’s departure would be like seeing “a friend walk off into the desert.”

But Mr. Van Rompuy also suggested that the strategy developed by Prime Minister David Cameron to restore dwindling public support for keeping Britain inside the bloc was likely to fail.

In an interview published Friday in The Guardian, a British daily, Mr. Van Rompuy said that renegotiation could undermine the one part of the European Union that Mr. Cameron says he values most: the single market under which around 500 million Europeans can do business without barriers.

“If every member state were able to cherry-pick those parts of existing policies that they most like, and opt out of those that they least like, the Union in general, and the single market in particular, would soon unravel,” he said.

The intervention from Mr. Van Rompuy highlights the fact that other nations are likely to resent a process under which Britain seeks to retain the parts of E.U. membership that it likes, while rejecting the rest. In order to renegotiate British membership terms, all other member states would have to agree on the changes.

And, if that sort of discussion begins, other countries may make demands too, including some that could weaken the single market which seeks to establish a level playing field on trading issues.

“All member states can, and do, have particular requests and needs that are always taken into consideration as part of our deliberations,” Mr. Van Rompuy said in the interview. “I do not expect any member state to seek to undermine the fundamentals of our cooperative system in Europe.”

Mr. Cameron argues that, to persuade euro-skeptical British voters to stay in the European Union, the country should loosen its political and social policy ties to the Union and refocus them around Europe’s single economic market. He wants to renegotiate the terms of British membership and seek approval for the result of that negotiation from the public, possibly in a referendum.

Britain formally joined in the process of European integration in 1973, when it acceded to the European Economic Community. Two years later, after a change of government and negotiations on the terms of membership, it held a referendum in which around two-thirds of those who voted elected to stay.

One theory in Britain is that the euro debt crisis presents a new opportunity to re-fashion the process of European integration because the 17 countries that use the single currency may need to rewrite the Union’s governing treaties in order to become more closely integrated. That could give Britain the chance to negotiate its looser relationship simultaneously as part of a grand bargain.

Mr. Van Rompuy suggested, however, that such a rewriting of the treaties might not happen because it might not be necessary.

“The treaties allow a considerable degree of flexibility and much can be done without needing to amend them,” he told The Guardian. “It is perfectly possible to write all kinds of provisions into the treaties, but amending them is a lengthy and cumbersome procedure needing the unanimous agreement of every single member government and ratification.”

Mr. Van Rompuy’s comments come at a sensitive moment, ahead of a widely anticipated speech by Mr. Cameron, expected in mid-January, during which he might make the promise of a referendum explicit. Many of his own lawmakers now want Mr. Cameron to promise a straight “in or out” vote, though he has so far resisted.

The political mood within Mr. Cameron’s Conservative Party has hardened against engagement with Europe, partly because of the rise in popular support for the U.K. Independence Party, which has campaigned for Britain to leave the European Union and for tighter immigration controls.

UKIP is expected to do well in the next elections to the European Parliament in 2014, which will be held under a proportional electoral system that favors smaller parties. The party is unlikely to win many, or even any, seats in British parliamentary elections, expected the following year, because these will be fought under a first-past-the post system that tends to favor mainstream parties.

The smaller party could, though, take enough votes from the Conservative Party to deprive it of the seats it will need to form the next government.

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Surgery Returns to NYU Langone Medical Center

Chang W. Lee/The New York Times

Senator Charles E. Schumer spoke at a news conference Thursday about the reopening of NYU Langone Medical Center.

NYU Langone Medical Center opened its doors to surgical patients on Thursday, almost two months after Hurricane Sandy overflowed the banks of the East River and forced the evacuation of hundreds of patients.

While the medical center had been treating many outpatients, it had farmed out surgery to other hospitals, which created scheduling problems that forced many patients to have their operations on nights and weekends, when staffing is traditionally low. Some patients and doctors had to postpone not just elective but also necessary operations for lack of space at other hospitals.

The medical center’s Tisch Hospital, its major hospital for inpatient services, between 30th and 34th Streets on First Avenue, had been closed since the hurricane knocked out power and forced the evacuation of more than 300 patients, some on sleds brought down darkened flights of stairs.

“I think it’s a little bit of a miracle on 34th Street that this happened so quickly,” Senator Charles E. Schumer of New York said Thursday.

Mr. Schumer credited the medical center’s leadership and esprit de corps, and also a tour of the damaged hospital on Nov. 9 by the administrator of the Federal Emergency Management Agency, W. Craig Fugate, whom he and others escorted through watery basement hallways.

“Every time I talk to Fugate there are a lot of questions, but one is, ‘How are you doing at NYU?’ ” the senator said.

The reopening of Tisch to surgery patients and associated services, like intensive care, some types of radiology and recovery room anesthesia, was part of a phased restoration that will continue. Besides providing an essential service, surgery is among the more lucrative of hospital services.

The hospital’s emergency department is expected to delay its reopening for about 11 months, in part to accommodate an expansion in capacity to 65,000 patient visits a year, from 43,000, said Dr. Andrew W. Brotman, its senior vice president and vice dean for clinical affairs and strategy.

In the meantime, NYU Langone is setting up an urgent care center with 31 bays and an observation unit, which will be able to treat some emergency patients. It will initially not accept ambulances, but might be able to later, Dr. Brotman said. Nearby Bellevue Hospital Center, which was also evacuated, opened its emergency department to noncritical injuries on Monday.

Labor and delivery, the cancer floor, epilepsy treatment and pediatrics and neurology beyond surgery are expected to open in mid-January, Langone officials said. While some radiology equipment, which was in the basement, has been restored, other equipment — including a Gamma Knife, a device using radiation to treat brain tumors — is not back.

The flooded basement is still being worked on, and electrical gear has temporarily been moved upstairs. Mr. Schumer, a Democrat, said that a $60 billion bill to pay for hurricane losses and recovery in New York and New Jersey was nearing a vote, and that he was optimistic it would pass in the Senate with bipartisan support. But the measure’s fate in the Republican-controlled House is far less certain.

The bill includes $1.2 billion for damage and lost revenue at NYU Langone, including some money from the National Institutes of Health to restore research projects. It would also cover Long Beach Medical Center in Nassau County, Bellevue, Coney Island Hospital and the Veterans Affairs hospital in Manhattan.

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Surgery Returns to NYU Langone Medical Center

Chang W. Lee/The New York Times

Senator Charles E. Schumer spoke at a news conference Thursday about the reopening of NYU Langone Medical Center.

NYU Langone Medical Center opened its doors to surgical patients on Thursday, almost two months after Hurricane Sandy overflowed the banks of the East River and forced the evacuation of hundreds of patients.

While the medical center had been treating many outpatients, it had farmed out surgery to other hospitals, which created scheduling problems that forced many patients to have their operations on nights and weekends, when staffing is traditionally low. Some patients and doctors had to postpone not just elective but also necessary operations for lack of space at other hospitals.

The medical center’s Tisch Hospital, its major hospital for inpatient services, between 30th and 34th Streets on First Avenue, had been closed since the hurricane knocked out power and forced the evacuation of more than 300 patients, some on sleds brought down darkened flights of stairs.

“I think it’s a little bit of a miracle on 34th Street that this happened so quickly,” Senator Charles E. Schumer of New York said Thursday.

Mr. Schumer credited the medical center’s leadership and esprit de corps, and also a tour of the damaged hospital on Nov. 9 by the administrator of the Federal Emergency Management Agency, W. Craig Fugate, whom he and others escorted through watery basement hallways.

“Every time I talk to Fugate there are a lot of questions, but one is, ‘How are you doing at NYU?’ ” the senator said.

The reopening of Tisch to surgery patients and associated services, like intensive care, some types of radiology and recovery room anesthesia, was part of a phased restoration that will continue. Besides providing an essential service, surgery is among the more lucrative of hospital services.

The hospital’s emergency department is expected to delay its reopening for about 11 months, in part to accommodate an expansion in capacity to 65,000 patient visits a year, from 43,000, said Dr. Andrew W. Brotman, its senior vice president and vice dean for clinical affairs and strategy.

In the meantime, NYU Langone is setting up an urgent care center with 31 bays and an observation unit, which will be able to treat some emergency patients. It will initially not accept ambulances, but might be able to later, Dr. Brotman said. Nearby Bellevue Hospital Center, which was also evacuated, opened its emergency department to noncritical injuries on Monday.

Labor and delivery, the cancer floor, epilepsy treatment and pediatrics and neurology beyond surgery are expected to open in mid-January, Langone officials said. While some radiology equipment, which was in the basement, has been restored, other equipment — including a Gamma Knife, a device using radiation to treat brain tumors — is not back.

The flooded basement is still being worked on, and electrical gear has temporarily been moved upstairs. Mr. Schumer, a Democrat, said that a $60 billion bill to pay for hurricane losses and recovery in New York and New Jersey was nearing a vote, and that he was optimistic it would pass in the Senate with bipartisan support. But the measure’s fate in the Republican-controlled House is far less certain.

The bill includes $1.2 billion for damage and lost revenue at NYU Langone, including some money from the National Institutes of Health to restore research projects. It would also cover Long Beach Medical Center in Nassau County, Bellevue, Coney Island Hospital and the Veterans Affairs hospital in Manhattan.

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China Toughens Restrictions on Internet Use

HONG KONG — The Chinese government issued new rules on Friday requiring Internet users to provide their real names to service providers, while assigning Internet companies greater responsibility for deleting forbidden postings and reporting them to the authorities.

The decision came as government censors have sharply stepped up restrictions on China’s international Internet traffic in recent weeks. The restrictions are making it harder for businesses to protect commercial secrets and for individuals to view overseas Web sites that the Chinese Communist Party deems politically sensitive.

The new regulations, issued by the Standing Committee of the National People’s Congress, allow Internet users to continue to adopt pseudonyms for their online postings, but only if they first provide their real names to service providers, a measure that could chill some of the vibrant discourse on the country’s Twitter-like microblogs. The authorities periodically detain and even jail Internet users for politically sensitive comments, such as calls for a multiparty democracy or accusations of impropriety by local officials.

Any entity providing Internet access, including over fixed-line or mobile phones, “should when signing agreements with users or confirming provision of services, demand that users provide true information about their identities,” the committee ordered.

In recent weeks, Internet users in China have exposed a series of sexual and financial scandals that have led to the resignations or dismissals of at least 10 local officials. International news media have also published a series of reports in recent months on the accumulation of wealth by the family members of China’s leaders, and some Web sites carrying such reports, including Bloomberg’s and the English- and Chinese-language sites of The New York Times, have been assiduously blocked, while Internet comments about them have been swiftly deleted.

The regulations issued Friday build on a series of similar administrative guidelines and municipal rules issued over the past year. China’s mostly private Internet service providers have been slow to comply with them, fearing the reactions of their customers. The committee’s decision has much greater legal force, and puts far more pressure on Chinese Internet providers to comply more quickly and more comprehensively, Internet specialists said.

In what appeared to be an effort to make the decision more palatable to the Chinese public, the committee also included a mandate for businesses in China to be more cautious in gathering and protecting electronic data.

“Nowadays on the Internet there are very serious problems with citizens’ personal electronic information being recklessly collected, used without approval, illegally disclosed, and even traded and sold,” Li Fei, a deputy director of the committee’s legislative affairs panel, said on Friday at a news conference in Beijing. “There are also a large number of cases of invasive attacks on information systems to steal personal electronic information, as well as lawbreaking on the Internet through swindles and through defaming and slandering others.”

Mr. Li denied that the government was seeking to prevent the exposure of corruption.

“When citizens exercise these rights according to the law, no organization or individual can use any reason or excuse to interfere, and cannot suppress them or exact revenge,” he said. “At the same time, when citizens exercise their rights, including through use of the Internet, they should stay within the bounds of the Constitution and the laws, and must not harm the legitimate rights and interests of the state, society, the collective or of other citizens.”

A spokesman for the National People’s Congress said that 145 members of the committee voted in favor of the new rules, with 5 abstaining and 1 voting against them.

The requirement for real names appeared to be aimed particularly at cellphone companies and other providers of mobile Internet access. At the news conference, an official from the Ministry of Industry and Information Technology, Zhao Zhiguo, said that nearly all fixed-line services now had real-name registration, but that only about 70 percent of mobile phones were registered under real names.

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Iran’s Only Female Cabinet Minister Dismissed

Iran’s president on Thursday dismissed his health minister, the only woman to serve in the cabinet since the 1979 Islamic revolution, after she publicly criticized the government’s response to acute shortages of medicine imports, an indirect consequence of the Western sanctions imposed on the country.

Accounts in the state-run news media of the dismissal of the minister, Marzieh Vahid-Dastjerdi, did not provide an explanation for it. Iran’s Press TV Web site said President Mahmoud Ahmadinejad had appointed a caretaker health minister, Mohammad Hassan Tariqat-Monfared, and had told him in a presidential decree that the reduction of people’s health care expenses was among “the main priorities of this important ministry.”

Dr. Vahid-Dastjerdi, a gynecologist, was appointed in 2009 and is considered an advocate of women’s rights in Iranian society. She spoke out last month, apparently angering the president, by saying that an allocation in the budget of foreign currency needed to purchase medicines abroad was inadequate.

“I have heard that luxury cars have been imported with subsidized dollars, but I don’t know what happened to the dollars that were supposed to be allocated for importing medicine,” Dr. Vahid-Dastjerdi said on state television, according to a translation of her remarks reported by Reuters.

Absent such an allocation, she said, it was necessary to impose a large increase in the price of medicines, which would add to the inflationary pressures already afflicting the economy because of a plunge in value this year of the Iranian currency, the rial. Mr. Ahmadinejad opposed the price increase.

Many economists have attributed the rial’s depreciation to Iran’s increased isolation, a consequence of the penalties imposed by the United States and European Union to pressure Iran to stop enriching uranium for its disputed nuclear energy program. Some of Mr. Ahmadinejad’s critics in Iran have also blamed the currency problems on what they call his economic mismanagement.

The medicine shortage in Iran has become an urgent problem because many Western-made drugs are increasingly hard to obtain. Under the sanctions, a broad Western ban on many financial transactions with Iran has dissuaded many foreign companies from doing business with the country, even though medicines are among items exempted from the sanctions.

Recently, the president of the Iranian Academy of Medical Sciences, Seyed Alireza Marandi, bitterly complained about the medical impact of the sanctions in a letter to Ban Ki-moon, the United Nations secretary general. Dr. Marandi called the sanctions brutal measures that had increased mortality rates “as a result of the unavailability of essential drugs and shortages of medical supplies and equipment,” according to a report by the Fars News Agency.

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Libraries Try to Update the Bookstore Model

Tyler Bissmeyer for The New York Times

Vicki Culler shops for discounted books at The Friends of the Public Library in Cincinnati.

At the bustling public library in Arlington Heights, Ill., requests by three patrons to place any title on hold prompt a savvy computer tracking system to order an additional copy of the coveted item. That policy was intended to eliminate the frustration of long waits to check out best sellers and other popular books. But it has had some unintended consequences, too: the library’s shelves are now stocked with 36 copies of “Fifty Shades of Grey.”

Of course, librarians acknowledge that when patrons’ passion for the sexy series lacking in literary merit cools in a year or two, the majority of volumes in the “Fifty Shades” trilogy will probably be plucked from the shelves and sold at the Friends of the Library’s used-book sales, alongside other poorly circulated, donated and out-of-date materials.

“A library has limited shelf space, so you almost have to think of it as a store, and stock it with the things that people want,” said Jason Kuhl, the executive director of the Arlington Heights Memorial Library. Renovations going on there now will turn a swath of the library’s first floor into an area resembling a bookshop, where patrons will be pampered with cozy seating, a vending cafe and, above all, an abundance of best sellers.

As librarians across the nation struggle with the task of redefining their roles and responsibilities in a digital age, many public libraries are seeing an opportunity to fill the void created by the loss of traditional bookstores. Indeed, today’s libraries are increasingly adapting their collections and services based on the demands of library patrons, whom they now call customers. Today’s libraries are reinventing themselves as vibrant town squares, showcasing the latest best sellers, lending Kindles loaded with e-books, and offering grassroots technology training centers. Faced with the need to compete for shrinking municipal finances, libraries are determined to prove they can respond as quickly to the needs of the taxpayers as the police and fire department can.

“I think public libraries used to seem intimidating to many people, but today, they are becoming much more user-friendly, and are no longer these big, impersonal mausoleums,” said Jeannette Woodward, a former librarian and author of “Creating the Customer-Driven Library: Building on the Bookstore Model.”

“Public libraries tread a fine line,” Ms. Woodward said. “They want to make people happy, and get them in the habit of coming into the library for popular best sellers, even if some of it might be considered junk. But libraries also understand the need for providing good information, which often can only be found at the library.”

Cheryl Hurley, the president of the Library of America, a nonprofit publisher in New York “dedicated to preserving America’s best and most significant writing,” said the trend of libraries that cater to the public’s demand for best sellers is not surprising, especially given the ravages of the recession on public budgets.

Still, Ms. Hurley remains confident that libraries will never relinquish their responsibility to also provide patrons with the opportunity to discover literary works of merit, be it the classics, or more recent fiction from novelists like Philip Roth, whose work is both critically acclaimed and immensely popular.

“The political ramifications for libraries today can result in driving the collection more and more from what the people want, rather than libraries shaping the tastes of the readers,” Ms. Hurley said. “But one of the joys of visiting the public library is the serendipity of discovering another book, even though you were actually looking for that best seller that you thought you wanted.”

“It’s all about balancing the library’s mission and its marketing, and that is always a tricky dance,” she added.

While print books, both fiction and nonfiction, still make up the bulk of most library collections – e-books remain limited to less than 2 percent of many collections in part because some publishers limit their availability at libraries — building renovation plans these days rarely include expanding shelf space for print products. Instead, many libraries are culling their collections and adapting floor plans to accommodate technology training programs, as well as mini-conference rooms that offer private, quiet spaces frequently requested by self-employed consultants meeting with clients, as well as teenagers needing space to huddle over group projects.

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Measles: Measles Epidemic Is Spreading in Central Africa

Jehad Nga for The New York Times

An internally displaced persons camp in Goma, in the Democratic Republic of Congo. In addition to recent violence in the country, a spreading measles epidemic is further endangering the lives of thousands of children there.

A large measles epidemic is spreading in Central Africa, endangering the lives of thousands of children, the medical charity Doctors Without Borders warned last week.

Since October, the charity has vaccinated more than 226,000 children in the eastern part of the Democratic Republic of Congo. The organization has also treated nearly 13,000 Congolese for the effects of the disease.

Measles is very contagious. In places where many children are malnourished and vitamin-deficient, it kills 1 percent to15 percent of those who don’t receive medical care, Doctors Without Borders estimated. (Even in the United States in the 1990s, although cases were rare, the fatality rate was 0.3 percent, according to the Centers for Disease Control and Prevention. In AIDS patients, the rate is 30 percent.)

The eastern Congo basin has serious shortages of medical workers and of drugs. While there is no treatment for measles itself, antibiotics can save those who develop pneumonia, meningitis or other secondary infections. Measles can also cause blindness by scarring the eyeball.

The outbreak is taking place despite enormous success against the disease worldwide. According to a study released earlier this year, deaths from measles have dropped by almost 75 percent since 2000.

Most of the lives saved were in Africa and India. Measles shots are often cited as one of the chief reasons that deaths of children under age 5 around the world have fallen steadily.

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Measles: Measles Epidemic Is Spreading in Central Africa

Jehad Nga for The New York Times

An internally displaced persons camp in Goma, in the Democratic Republic of Congo. In addition to recent violence in the country, a spreading measles epidemic is further endangering the lives of thousands of children there.

A large measles epidemic is spreading in Central Africa, endangering the lives of thousands of children, the medical charity Doctors Without Borders warned last week.

Since October, the charity has vaccinated more than 226,000 children in the eastern part of the Democratic Republic of Congo. The organization has also treated nearly 13,000 Congolese for the effects of the disease.

Measles is very contagious. In places where many children are malnourished and vitamin-deficient, it kills 1 percent to15 percent of those who don’t receive medical care, Doctors Without Borders estimated. (Even in the United States in the 1990s, although cases were rare, the fatality rate was 0.3 percent, according to the Centers for Disease Control and Prevention. In AIDS patients, the rate is 30 percent.)

The eastern Congo basin has serious shortages of medical workers and of drugs. While there is no treatment for measles itself, antibiotics can save those who develop pneumonia, meningitis or other secondary infections. Measles can also cause blindness by scarring the eyeball.

The outbreak is taking place despite enormous success against the disease worldwide. According to a study released earlier this year, deaths from measles have dropped by almost 75 percent since 2000.

Most of the lives saved were in Africa and India. Measles shots are often cited as one of the chief reasons that deaths of children under age 5 around the world have fallen steadily.

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Senate Leader Says Deal Is Unlikely Before Fiscal Deadline

WASHINGTON — Senator Harry Reid of Nevada, the majority leader, warned Thursday that there was scant time to put together a Congressional deal to avert the impending fiscal crisis and that no resolution was in sight.

T.J. Kirkpatrick for The New York Times

Senator Harry Reid arrived at the Capitol on Thursday in Washington.

“I have to be very honest,” Mr. Reid said as the Senate convened in an unusual session between Christmas and New Year’s Day. “I don’t know time-wise how it can happen now.”

Mr. Reid offered his pessimistic assessment shortly before President Obama, cutting his vacation short, arrived back in Washington on Air Force One. White House officials said that before leaving Hawaii, Mr. Obama had spoken separately by phone with each of the four Congressional leaders about the status of negotiations, but they gave no details of the discussion.

Mr. Obama is expected to invite all four lawmakers to meet on Friday. In a related development, House Republicans were told to return to Washington on Sunday. Republican senators were planning to convene at the Capitol — normally somnolent during Christmas week — to strategize.

On the Senate floor Thursday, Mr. Reid excoriated House Republicans for failing to consider a Senate-passed measure that would extend lower tax rates on household income up to $250,000. He urged House members to return to the Capitol to put together at least a modest deal to avoid the more than half-a-trillion dollars in automatic tax increases and spending cuts set to begin in January.

“The American people are waiting for the ball to drop,” Mr. Reid said, “but it’s not going to be a good drop.”

A spokesman for Senator Mitch McConnell, Republican of Kentucky and the minority leader, confirmed that he had spoken with the president, and said that Mr. McConnell was “happy to review what the president has in mind.” But the spokesman, Don Stewart, said Senate Democrats had not come ahead with a plan.

“When they do, members on both sides of the aisle will review the legislation and make decisions on how best to proceed,” Mr. Stewart said.

Mr. Reid said that absent a move from Republicans, the Senate would move forward this week on a national security measure concerning espionage, as well as a bill to help states that have suffered hurricane damage, with multiple votes possible.

“We are here in Washington working,” Mr. Reid said, “while the members of the House of Representatives are out watching movies and watching their kids play soccer and basketball and doing all kinds of things. They should be here.”

Senators, frustrated, pessimistic and in some cases downright miserable, returned to Washington with no clear fiscal agenda. Senator Ben Nelson, a retiring Democrat of Nebraska, arrived shortly after midnight on Thursday on a flight that was delayed more than four hours. As he walked through the airport, he lamented the deteriorating political comity that he has observed during two terms in the Senate and two terms as a Democratic governor of a conservative state.

“There are folks who are elected who have come here with an agenda to do nothing and want to stop everything,” Mr. Nelson said in an interview. “It may be the new norm – blocking everything.”

For Mr. Nelson, who decided against seeking a third term, the looming fiscal crisis would be the final legislative act of a political career built around a bipartisan voting record. He said he was not confident that a real deal could be reached that would be acceptable to both sides, considering that Congress is filled with many people “who didn’t accept the 2008 presidential election and haven’t accepted the 2012 election either.”

Jeff Zeleny contributed reporting.

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United Arab Emirates Arrests Suspects in Terror Plots

DUBAI, United Arab Emirates (Reuters) — Security forces in the United Arab Emirates have arrested members of a cell made up of militants from Saudi Arabia and the emirates who were planning to carry out attacks in both countries and in other states, the official Emirates News Agency said on Wednesday.

The federation of seven emirates, a major oil exporter and an ally of the United States, has had no attacks by Al Qaeda or other terrorist groups. But Islamist sentiment has risen in recent years, and Dubai, a business and tourism hub that attracts many Westerners, could make an attractive target for militants, analysts say.

The suspects had acquired materials and equipment for use in what the news agency called terrorist operations.

“The security authorities in the U.A.E., in coordination with the related security parties in Saudi Arabia, announced the arrest of an organized cell from the deviant group that was planning to carry out actions against national security of both countries and some brotherly states,” the agency said, without elaborating.

The phrase “deviant group” is often used by the authorities in Saudi Arabia to describe Al Qaeda.

In August, the Saudi authorities arrested a group of militants in Riyadh — mostly Yemeni nationals — suspected of having links to Al Qaeda. Thousands of people believed to be militants have been arrested since dozens were killed in terrorist attacks between 2003 and 2006 on Saudi residential compounds and offices for foreign workers and on government facilities.

The United States has poured aid into Yemen to stem the threat of attacks from the group Al Qaeda in the Arabian Peninsula and to try to prevent any spillover of violence into Saudi Arabia, the world’s top oil exporter.

In 2010, Al Qaeda in the Arabian Peninsula, formed with the merger of Al Qaeda’s Yemeni and Saudi branches, said it was behind a plot to send two parcel bombs to the United States. The bombs were intercepted in Britain and Dubai.

Though the emirates have escaped much of the upheaval that has shaken the Arab world, the authorities have moved swiftly to stem any sign of political dissent, detaining more than 60 Islamists this year over suspected threats to state security and links to foreign groups.

Those detainees, who belong to an Islamist group called Al-Islah, have confessed to setting up a secret organization with an armed force whose aim was to take power and establish an Islamic state, the local news media reported in September. The group denied the accusations.

Many of the detained Islamists are from the more religiously conservative northern emirates like Sharjah and Ras al-Khaimah, which produced one of the Sept. 11 hijackers.

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State of the Art: Pogie Awards for the Brightest Ideas of 2012

Good evening, and welcome to The Dalles, Ore.! Here in the cafetorium of the James A. Garfield Middle School, we meet every year for the biggest event in technology: the Pogie awards!

We don’t award these coveted trophies to the best products of the year; everybody does that. No, the Pogies celebrate the best ideas of the year: ingenious features that somehow made it past the lawyers, through the penny-pinching committees and into real-world tech gadgets — even if the products overall are turkeys.

So now, for the eighth straight year — the FedEx envelopes, please!

SMART STAY On Samsung’s Galaxy S III phone, the front-facing camera looks for your eyes. When you’re not looking at the screen, it dims to save battery power. It brightens right back up when you return your gaze. So smart.

POWER NAP Most of the world’s laptops do exactly one thing when you close their lids: sleep. All other activity stops.

But Apple asked: Why? Why can’t network activity keep chugging away even when the lid is closed? Why can’t your laptop keep backing itself up, downloading e-mail and syncing its online data (calendars, calendar notes, reminders, photos)?

That is the idea behind Power Nap, a feature of OS X Mountain Lion that works on recent MacBook models. You can wake up, grab your laptop and head out, confident that it is backed up and has all your latest mail downloaded.

SLIPSTREAM On Amazon’s 8.9-inch Kindle HD, something ingenious happens when you call up a big-name Web site: It pops onto your screen fast, all at once. It’s almost as though the Kindle’s browser is loading a JPEG screenshot of a Web page, rather than the dozens of individual graphics, text bits and other elements that constitute a Web page.

And that’s exactly what it is doing. Behind the scenes, Amazon’s servers grab frequent screenshots of the most popular Web sites; when you visit one, what you see first is that JPEG image (with live links in the right places, fortunately).

While you are studying that image, the browser continues to fetch the component pieces of the page — and after a few seconds, a blink (and occasionally a shifted element) lets you know that you are now looking at the real deal. It is a sneaky, logical, brilliant trick that saves you time and costs you nothing.

CYCLORAMIC Just when you think that nobody could possibly have another fresh idea for a phone app, Cycloramic ($1) makes 360-degree panoramic videos — without a tripod or swivel.

You stand the phone upright and tap the Go button. Incredibly, the phone, balancing on its end, begins to rotate itself. Freakiest darned thing you ever saw. Great for winning bar bets or establishing new religions.

If you’ve ever seen a phone scoot itself along a table when it is in buzz mode, you get the principle. The app triggers the phone’s vibration module at exactly the right frequencies to make the phone turn on the table. The phone’s sensors figure out how far it’s rotated.

It works only on shiny surfaces like glass, polished granite or laminated wood (like desks), and only the iPhone 5 has exactly the right balance. It’s a jaw-dropper.

ELECTRONIC LEASHES The Ciago iAlert and Cobra Tag are Bluetooth keychain fobs that communicate with your iPhone or Android phone. Once you’re 30 feet away from the phone, the keychain starts beeping, as though to say, “You’re leaving your $200 phone behind, you idiot!” It works the other way, too; the phone beeps if you leave your keys behind.

In practice, these fobs are cheaply built and, if the Amazon reviews are to be believed, not always reliable. But remember — on the night of the Pogies, it’s the idea that counts.

BLUETOOTH 4.0 Bluetooth is that wireless technology that connects gadgets within 30 feet — your phone to your headset, for example — and kills your battery charge. Right?

Actually, it doesn’t anymore. Bluetooth 4.0, built into the latest iPhone and Android phones, is also called Bluetooth LE (low energy) for a reason. For the most part, it uses power only when it has data to exchange. The rest of the time, it sleeps.

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Well: Exercise and the Ever-Smarter Human Brain

Anyone whose resolve to exercise in 2013 is a bit shaky might want to consider an emerging scientific view of human evolution. It suggests that we are clever today in part because a million years ago, we could outrun and outwalk most other mammals over long distances. Our brains were shaped and sharpened by movement, the idea goes, and we continue to require regular physical activity in order for our brains to function optimally.

Phys Ed

Gretchen Reynolds on the science of fitness.

The role of physical endurance in shaping humankind has intrigued anthropologists and gripped the popular imagination for some time. In 2004, the evolutionary biologists Daniel E. Lieberman of Harvard and Dennis M. Bramble of the University of Utah published a seminal article in the journal Nature titled “Endurance Running and the Evolution of Homo,” in which they posited that our bipedal ancestors survived by becoming endurance athletes, able to bring down swifter prey through sheer doggedness, jogging and plodding along behind them until the animals dropped.

Endurance produced meals, which provided energy for mating, which meant that adept early joggers passed along their genes. In this way, natural selection drove early humans to become even more athletic, Dr. Lieberman and other scientists have written, their bodies developing longer legs, shorter toes, less hair and complicated inner-ear mechanisms to maintain balance and stability during upright ambulation. Movement shaped the human body.

But simultaneously, in a development that until recently many scientists viewed as unrelated, humans were becoming smarter. Their brains were increasing rapidly in size.

Today, humans have a brain that is about three times larger than would be expected, anthropologists say, given our species’ body size in comparison with that of other mammals.

To explain those outsized brains, evolutionary scientists have pointed to such occurrences as meat eating and, perhaps most determinatively, our early ancestors’ need for social interaction. Early humans had to plan and execute hunts as a group, which required complicated thinking patterns and, it’s been thought, rewarded the social and brainy with evolutionary success. According to that hypothesis, the evolution of the brain was driven by the need to think.

But now some scientists are suggesting that physical activity also played a critical role in making our brains larger.

To reach that conclusion, anthropologists began by looking at existing data about brain size and endurance capacity in a variety of mammals, including dogs, guinea pigs, foxes, mice, wolves, rats, civet cats, antelope, mongeese, goats, sheep and elands. They found a notable pattern. Species like dogs and rats that had a high innate endurance capacity, which presumably had evolved over millenniums, also had large brain volumes relative to their body size.

The researchers also looked at recent experiments in which mice and rats were systematically bred to be marathon runners. Lab animals that willingly put in the most miles on running wheels were interbred, resulting in the creation of a line of lab animals that excelled at running.

Interestingly, after multiple generations, these animals began to develop innately high levels of substances that promote tissue growth and health, including a protein called brain-derived neurotrophic factor, or BDNF. These substances are important for endurance performance. They also are known to drive brain growth.

What all of this means, says David A. Raichlen, an anthropologist at the University of Arizona and an author of a new article about the evolution of human brains appearing in the January issue of Proceedings of the Royal Society Biology, is that physical activity may have helped to make early humans smarter.

“We think that what happened” in our early hunter-gatherer ancestors, he says, is that the more athletic and active survived and, as with the lab mice, passed along physiological characteristics that improved their endurance, including elevated levels of BDNF. Eventually, these early athletes had enough BDNF coursing through their bodies that some could migrate from the muscles to the brain, where it nudged the growth of brain tissue.

Those particular early humans then applied their growing ability to think and reason toward better tracking prey, becoming the best-fed and most successful from an evolutionary standpoint. Being in motion made them smarter, and being smarter now allowed them to move more efficiently.

And out of all of this came, eventually, an ability to understand higher math and invent iPads. But that was some time later.

The broad point of this new notion is that if physical activity helped to mold the structure of our brains, then it most likely remains essential to brain health today, says John D. Polk, an associate professor of anthropology at the University of Illinois at Urbana-Champaign, and co-author, with Dr. Raichlen, of the new article.

And there is scientific support for that idea. Recent studies have shown, he says, that “regular exercise, even walking,” leads to more robust mental abilities, “beginning in childhood and continuing into old age.”

Of course, the hypothesis that jogging after prey helped to drive human brain evolution is just a hypothesis, Dr. Raichlen says, and almost unprovable.

But it is compelling, says Harvard’s Dr. Lieberman, who has worked with the authors of the new article. “I fundamentally agree that there is a deep evolutionary basis for the relationship between a healthy body and a healthy mind,” he says, a relationship that makes the term “jogging your memory” more literal than most of us might have expected and provides a powerful incentive to be active in 2013.

Read More..

Well: Exercise and the Ever-Smarter Human Brain

Anyone whose resolve to exercise in 2013 is a bit shaky might want to consider an emerging scientific view of human evolution. It suggests that we are clever today in part because a million years ago, we could outrun and outwalk most other mammals over long distances. Our brains were shaped and sharpened by movement, the idea goes, and we continue to require regular physical activity in order for our brains to function optimally.

Phys Ed

Gretchen Reynolds on the science of fitness.

The role of physical endurance in shaping humankind has intrigued anthropologists and gripped the popular imagination for some time. In 2004, the evolutionary biologists Daniel E. Lieberman of Harvard and Dennis M. Bramble of the University of Utah published a seminal article in the journal Nature titled “Endurance Running and the Evolution of Homo,” in which they posited that our bipedal ancestors survived by becoming endurance athletes, able to bring down swifter prey through sheer doggedness, jogging and plodding along behind them until the animals dropped.

Endurance produced meals, which provided energy for mating, which meant that adept early joggers passed along their genes. In this way, natural selection drove early humans to become even more athletic, Dr. Lieberman and other scientists have written, their bodies developing longer legs, shorter toes, less hair and complicated inner-ear mechanisms to maintain balance and stability during upright ambulation. Movement shaped the human body.

But simultaneously, in a development that until recently many scientists viewed as unrelated, humans were becoming smarter. Their brains were increasing rapidly in size.

Today, humans have a brain that is about three times larger than would be expected, anthropologists say, given our species’ body size in comparison with that of other mammals.

To explain those outsized brains, evolutionary scientists have pointed to such occurrences as meat eating and, perhaps most determinatively, our early ancestors’ need for social interaction. Early humans had to plan and execute hunts as a group, which required complicated thinking patterns and, it’s been thought, rewarded the social and brainy with evolutionary success. According to that hypothesis, the evolution of the brain was driven by the need to think.

But now some scientists are suggesting that physical activity also played a critical role in making our brains larger.

To reach that conclusion, anthropologists began by looking at existing data about brain size and endurance capacity in a variety of mammals, including dogs, guinea pigs, foxes, mice, wolves, rats, civet cats, antelope, mongeese, goats, sheep and elands. They found a notable pattern. Species like dogs and rats that had a high innate endurance capacity, which presumably had evolved over millenniums, also had large brain volumes relative to their body size.

The researchers also looked at recent experiments in which mice and rats were systematically bred to be marathon runners. Lab animals that willingly put in the most miles on running wheels were interbred, resulting in the creation of a line of lab animals that excelled at running.

Interestingly, after multiple generations, these animals began to develop innately high levels of substances that promote tissue growth and health, including a protein called brain-derived neurotrophic factor, or BDNF. These substances are important for endurance performance. They also are known to drive brain growth.

What all of this means, says David A. Raichlen, an anthropologist at the University of Arizona and an author of a new article about the evolution of human brains appearing in the January issue of Proceedings of the Royal Society Biology, is that physical activity may have helped to make early humans smarter.

“We think that what happened” in our early hunter-gatherer ancestors, he says, is that the more athletic and active survived and, as with the lab mice, passed along physiological characteristics that improved their endurance, including elevated levels of BDNF. Eventually, these early athletes had enough BDNF coursing through their bodies that some could migrate from the muscles to the brain, where it nudged the growth of brain tissue.

Those particular early humans then applied their growing ability to think and reason toward better tracking prey, becoming the best-fed and most successful from an evolutionary standpoint. Being in motion made them smarter, and being smarter now allowed them to move more efficiently.

And out of all of this came, eventually, an ability to understand higher math and invent iPads. But that was some time later.

The broad point of this new notion is that if physical activity helped to mold the structure of our brains, then it most likely remains essential to brain health today, says John D. Polk, an associate professor of anthropology at the University of Illinois at Urbana-Champaign, and co-author, with Dr. Raichlen, of the new article.

And there is scientific support for that idea. Recent studies have shown, he says, that “regular exercise, even walking,” leads to more robust mental abilities, “beginning in childhood and continuing into old age.”

Of course, the hypothesis that jogging after prey helped to drive human brain evolution is just a hypothesis, Dr. Raichlen says, and almost unprovable.

But it is compelling, says Harvard’s Dr. Lieberman, who has worked with the authors of the new article. “I fundamentally agree that there is a deep evolutionary basis for the relationship between a healthy body and a healthy mind,” he says, a relationship that makes the term “jogging your memory” more literal than most of us might have expected and provides a powerful incentive to be active in 2013.

Read More..

Irish Travelers, Gathering for Christmas, Flood a Town

RATHKEALE, Ireland — Christmas in Ireland is a time of homecomings, with joyous family reunions at airports and ferry piers. But the largest single gathering of all briefly turns this little town into the only place in Ireland where armed police officers patrol the streets 24 hours a day to deter internecine feuds and other disorderly conduct.

Usually, Rathkeale is an unremarkable rural town in County Limerick, but every year at this time, cavalcades of Irish nomads — known as travelers — return here to the place they regard as their spiritual home. It is an opportunity to hold fairy-tale weddings and christenings, and to settle old scores. The highly mobile families are deeply interwoven through marriage and kinship, and extremely suspicious of outsiders and the authorities.

For about six weeks of the year, the town’s population swells to 4,500 from 1,500, and ostentatious displays of wealth are common. Expensive sport utility vehicles create gridlock in the narrow streets and alleyways, trailers and mobile homes clutter the sidewalks and young men speed through the surrounding country lanes in their sports cars.

A long history of violence between clans hangs like a cloud over the travelers. When they congregate at Christmas, brawls involving knives, cudgels, iron bars and screwdrivers have been known to erupt, and traffic violations multiply. Last year alone, the police seized 30 vehicles for various offenses.

Over the past couple of decades, the travelers have bought or built houses in Rathkeale. The rows of extravagant, mock-Georgian mansions that have sprung up just off the main street are boarded up for most of the year but come alive around Christmas when their owners return, mainly from Britain but also from increasingly far-flung places.

The Rathkeale travelers have long had a reputation for business acumen, making fortunes by developing property, dealing antiques, trading in scrap metal and asphalt paving. But in recent years, a growing body of evidence has fueled suspicions that not all of the money flowing into Rathkeale comes from strictly legal transactions and that the property deals are a form of money laundering.

“People won’t say a bad word against them in public because they’re afraid of getting a bottle through the window — or something a lot worse,” said one Rathkeale resident, who did not want to be named. “Who really believes tarring driveways or fixing gutters gets you those massive houses or flashy cars?”

Certainly, travelers with links to Rathkeale have made headlines for all the wrong reasons in recent years.

Five members of one family were sentenced to prison this month after being found guilty of forcing vulnerable men to work for them under virtually slavelike conditions. According to court documents, the British police believe that the family owns several properties in Rathkeale, and the British authorities are working with their Irish counterparts to seize the family’s assets.

Others with Rathkeale connections have been jailed for various offenses from Australia to Iceland, including smuggling and handling counterfeit goods. In 2010, two men were caught trying to buy illegal black rhino horns from undercover federal agents.

Edward Grace, the deputy chief of law enforcement with the United States Fish and Wildlife Service, said the agency expected “more indictments of members of the Rathkeale Irish Traveler group.”

“These Irish Traveler gang members are the middlemen in the operation that also involves Chinese and Asian gangs,” he said. “They have access to large amounts of cash to buy the horns, and they have the network to sell them on at exorbitant prices. Some people will say, ‘What’s the harm here? These animals are already dead.’ But they are fueling an illegal trade and that means more incentive to kill endangered species.”

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Chicken Farms Try Oregano as Antibiotic Substitute

Jessica Kourkounis for The New York Times

Bell & Evans' chickens at a farm in Pennsylvania. Products at Bell & Evans have long been free of antibiotics, contributing to the company’s financial success as consumers have demanded purer foods.

FREDERICKSBURG, Pa. — The smell of oregano wafting from Scott Sechler’s office is so strong that anyone visiting Bell & Evans these days could be forgiven for wondering whether Mr. Sechler has forsaken the production of chicken and gone into pizza.

Oregano lies loose in trays and tied into bunches on tabletops and counters, and a big, blue drum that held oregano oil stands in the corner. “Have you ever tried oregano tea?” Mr. Sechler asked, mashing leaves between his broad fingers.

Off and on over the last three years or so, his chickens have been eating a specially milled diet laced with oregano oil and a touch of cinnamon. Mr. Sechler swears by the concoction as a way to fight off bacterial diseases that plague meat and poultry producers without resorting to antibiotics, which some experts say can be detrimental to the humans who eat the meat. Products at Bell & Evans, based in this town about 30 miles east of Harrisburg, have long been free of antibiotics, contributing to the company’s financial success as consumers have demanded purer foods.

But Mr. Sechler said nothing he had used as a substitute in the past worked as well as oregano oil. “I have worried a bit about how I’m going to sound talking about this,” he said. “But I really do think we’re on to something here.”

Skeptics of herbal medicines abound, as any quick Internet search demonstrates. “Oil of oregano is a perennial one, advertised as a cure for just about everything,” said Scott Gavura, a pharmacist in Toronto who writes for the Web site Science-Based Medicine. “But there isn’t any evidence, there are too many unanswered questions and the only proponents for it are the ones producing it.”

Nonetheless, Mr. Gavura said he would welcome a reduction in the use of antibiotics in animals. At the same time, consumers are growing increasingly sophisticated about the content of the foods they eat.

Data on sales of antibiotic-free meat is hard to come by, but the sales are a tiny fraction of the overall meat market. Sales in the United States of organic meat, poultry and fish, which by law must be raised without antibiotics, totaled $538 million in 2011, according to the Organic Trade Association. By comparison, sales of all beef that year were $79 billion.

Still, retailers like Costco, Whole Foods and Trader Joe’s, as well as some restaurant chains, complain that they cannot get enough antibiotic-free meat.

Noodles & Company, a fast-growing chain of more than 300 restaurants, recently added antibiotic-free pork to the choices of ingredients that customers can add to their made-to-order pastas. It ensured its supply by ordering cuts of meat that were not in relatively high demand and by committing in advance to buy a year’s worth, said Dan Fogarty, its executive vice president for marketing.

“We’re deliberately voting with our pocketbooks,” he said.

In a nationwide telephone survey of 1,000 adults in March, more than 60 percent told the Consumer Reports National Research Center that they would be willing to pay at least 5 cents a pound more for meat raised without antibiotics.

“Before, it was kind of a nice little business, and while it’s still microscopic in the grand scheme of things, we’re seeing acceptance from retailers across the country, not just in California and on the East Coast,” said Stephen McDonnell, founder and chief executive of Applegate, an organic and natural meats company.

Mr. McDonnell said a confluence of trends, from heightened interest in whole and natural foods to growing concerns about medical problems like diabetes, obesity and gluten allergies, were contributing to the demand for antibiotic-free meat.

There is growing concern among health care experts and policy makers about antibiotic resistance and the rise of “superbugs,” bacteria that are impervious to one or more antibiotics. Those bacteria can be passed on to consumers, who eat meat infected with them and then cannot be treated.

In November, the Centers for Disease Control and Prevention and 25 national health organizations and advocacy groups issued a statement on antibiotics that, among other things, called for “limiting the use of medically important human antibiotics in food animals” and “supporting the use of such antibiotics in animals only for those uses that are considered necessary for assuring animal health.”

In 2011, there were several prominent recalls involving bacterial strains that are resistant to antibiotics, including more than 60 million pounds of ground beef contaminated with salmonella Typhimurium and about 36 million pounds of ground turkey spoiled with salmonella Heidelberg.

Consumer Reports released a study last month that found the bacteria Yersinia enterocolitica in 69 percent of 198 pork chop and ground pork samples bought at stores around the country. Some of the bacteria were resistant to one or more antibiotics.

Analysis of Food and Drug Administration data by the Center for Science in the Public Interest found that 80 percent of all antibiotics sold in the United States are used in animals. The majority of those antibiotics are used to spur growth or prevent infections from spreading in the crowded conditions in which most animal production takes place today.

The European Union has banned the use of antibiotics to accelerate growth, and the European Parliament is pushing to end their use as tools to prevent disease as well.

The oregano oil product Mr. Sechler uses, By-O-Reg Plus, is made by a Dutch company, Ropapharm International. In the late 1990s, Bayer conducted trials on the product, known as Ropadiar in Europe, comparing its ability to control diarrhea in piglets caused by E. coli with that of four of the company’s products.

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U.S. Civilian Is Killed at Police Headquarters in Kabul

KABUL, Afghanistan — A female police sergeant shot and killed an American civilian adviser at police headquarters in Kabul on Monday, Afghan police officials said, breaking a relative lull in the so-called insider killings that have strained the relationship between Americans and Afghans here.

The American victim was identified as Joseph Griffin, 49, of Mansfield, Ga., who had worked for DynCorp International as a police trainer since July 2011, according to a DynCorp spokeswoman, Ashley Burke.

Afghan officials identified the suspect as a woman named Nargis, a 33-year-old sergeant in the national police force who worked in the Interior Ministry’s legal and gender equality department, and whose husband is also a member of the police force.

A person at Kabul police headquarters, speaking on the condition of anonymity because he was not authorized to release information, said the attacker had shot the American adviser in the head at close range with a pistol and then was immediately arrested by other Afghan police officers. The person added that both American and Afghan officials were questioning her, and he said she was distraught. The police said they did not believe the attack was related to terrorism and that the suspect had no known connections with insurgents.

The Afghan news station TOLO cited Afghan officials as saying that the woman, who had crossed multiple police checkpoints before she fired her gun, had graduated from the national police academy in 2008, in one of its first female classes.

The effort to recruit and train female police officers has been fraught with difficulty. Eupol, the European police organization active in police training here, says there are only 380 female police officers in Kabul, and even fewer in the provinces, despite a goal by the Interior Ministry of recruiting 5,000 by the end of 2014.

Insider attacks, in which members of the Afghan security services have turned against their foreign allies, have greatly increased in the past year, with 61 American and other coalition members killed, not including the episode on Monday, compared with 35 deaths the previous year, according to NATO figures.

Monday’s attack — the first insider attack known to be committed by a woman — came after a lull in insider shootings after the military instituted a series of precautions meant to reduce them. The most recent episode was on Nov. 11, when a British soldier was killed in Helmand Province.

American and Afghan officials have been struggling to figure out how large a factor Taliban infiltration or coercion has been in such attacks. Although insurgent contact has been clear in some cases, many of the attacks have seemed to come out of personal animosity or outrage, attributed to culture clash or growing Afghan anger at what they see as an unwelcome occupation by the United States and its allies.

“The loss of any team member is tragic, but to have this happen over the holidays makes it seem all the more unfair,” Steven F. Gaffney, the chairman of DynCorp, said in a statement.

The company also released a statement attributed to the victim’s wife, Rennae Griffin. “My husband was a thoughtful, kind, generous and loving man who was selfless in all his actions and deeds,” it said.

In other violence on Monday, a coalition member was killed in an insurgent attack in eastern Afghanistan, and an Afghan Local Police commander killed five fellow officers at a checkpoint in Jowzjan Province in the north. Dur Mohammad, the commander at the checkpoint, shot and killed five officers under his command, according to Gen. Abdul Aziz Ghairat, the provincial police chief. He said the commander fled after the shooting. General Ghairat did not offer a motive, but said that Mr. Mohammad had connections with the Taliban in the area.

The Afghan Local Police program, which seeks to bring armed elements — including some former insurgents — into government service, has drawn criticism because of a series of episodes in which the armed elements have switched allegiances, sometimes repeatedly.

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Bits Blog: Instagram Does an About-Face

11:14 p.m. | Updated
SAN FRANCISCO — In the aftermath of the uproar over changes to Instagram’s privacy policy and terms of service earlier this week, the company did an about-face late Thursday.

In a blog post on the company’s site, Kevin Systrom, Instagram’s co-founder, said that where advertising was concerned, the company would revert to its previous terms of service, which have been in effect since October 2010.

“Rather than obtain permission from you to introduce possible advertising products we have not yet developed,” he wrote, “we are going to take the time to complete our plans, and then come back to our users and explain how we would like for our advertising business to work.” Users had been particularly concerned by a clause in Instagram’s policy introduced on Monday that suggested Instagram would share users’ data — like their favorite places, bands, restaurants and hobbies — with Facebook and its advertisers to better target ads.

They also took issue with an update to the company’s terms of service that suggested users’ photos could be used in advertisements, without compensation and even without their knowledge.

The terms of that user agreement said, “You agree that a business or other entity may pay us to display your user name, likeness, photos (along with any associated metadata) and/or actions you take, in connection with paid or sponsored content or promotions, without any compensation to you.”

Following a reaction that included customers defecting to other services, Mr. Systrom told Instagram users on Tuesday that the new policy had been misinterpreted. “It is our mistake that this language is confusing,” he wrote, and he promised an updated agreement.

That statement apparently was not enough. With more people leaving the service, the company, which Facebook bought for $735 million this year, reacted again by returning to the old rules.

Acknowledging those concerns late Thursday, Mr. Systrom wrote: “I want to be really clear: Instagram has no intention of selling your photos, and we never did. We don’t own your photos — you do.”

Mr. Systrom said the company would still be tweaking its privacy policy to quell users’ fears that their photos might pop-up on third-party sites without their consent.

But Mr. Systrom did not clarify how Instagram planned to monetize its service in the future. Facebook is under pressure to make Instagram earn income.

“It’s a free service — they have to monetize somewhere,” said John Casasanta, a principal at Tap Tap Tap, the maker of Camera+, a photo-filter app that has shunned advertising and instead charges users for premium features. “The days of the simple banner ads are gone. Their user data is too valuable.”

It was unclear whether reverting its terms of service would be enough to satisfy high-profile users like National Geographic, which stopped using its Instagram account in light of the moves, or other users who have aired their grievances on Twitter and Facebook.

The controversy has driven traffic and new users to several other photo-sharing applications.

Pheed, an Instagram-like app that gives users the option to monetize their own content by charging followers to see their posts, gained more users than any other app in the United States on Thursday. By Thursday morning, Pheed had jumped to the ninth most downloaded social-networking app in Apple’s iTunes store, just ahead of LinkedIn.

O. D. Kobo, Pheed’s chief executive, said Thursday morning that subscriptions to the service had quadrupled this week and that in the last 24 hours users had uploaded 300,000 new files to the service — more uploads than any other 24-hour-period since Pheed made its debut six weeks ago.

Another runaway success was Flickr, Yahoo’s photo-sharing service, which redesigned its app last week to make it easier to share photos on Twitter. In a stroke of good fortune, it released the app to positive reviews just as Instagram announced it would no longer sync with Twitter, a Facebook rival.

The day before Instagram announced changes to its terms of service, Flickr’s mobile app was ranked at around 175 in Apple’s overall iTunes app charts. Since that day, the application skyrocketed to the high 20s.

Of course, most of these services are still tiny compared to Instagram, which claims to have more than 100 million members who have uploaded upward of 5 billion photos using its service. And it was unclear if the services’ newfound members had also deleted their Instagram accounts or were merely dabbling in other offerings. But the migration, whether temporary or permanent, was a reminder of the volatility of success and that the fall to bottom can sometimes be as swift as the rise to the top.

Facebook and Instagram declined to say whether they had seen any significant number of account deletions or if they were concerned about losing ground in the photo-sharing market to rivals. Some photo apps took direct aim at Instagram. Camera+ even went so far as to include a snide, holiday-themed reference to Instagram’s stumbles in an app update on Wednesday.

“We’ll never do shady things with your shared pics, because it just isn’t right,” the update noted. “On that note, happy Christmas to all, and to all a good night!”

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Books: From Bang to Whimper: A Heart Drug’s Story

On June 23, 2005, American medicine managed to take a small step forward and a giant step backward at precisely the same time, with government approval of the first medication to be earmarked for a specific racial group. It was BiDil, a drug designed to treat heart failure in blacks.

Enthusiasts hailed BiDil’s approval by the Food and Drug Administration as a landmark event in the nascent field of pharmacogenomics, which aims to create drugs tailored to fit an individual’s genetic makeup as precisely as a bespoke suit drapes its owner’s shoulders. Critics just winced and clocked one more misstep in medicine’s long history of race-related disasters.

You would think that the elucidation of the human genome would have cleared up most of the hoary untruths surrounding race and health. But as Jonathan Kahn makes clear in his worthy if convoluted review of the events surrounding the birth of BiDil, the genome has in many respects only made things worse.

It has been clear for decades that race has minimal relevance to the body’s inner workings. Research has repeatedly shown that the biologic variations among individuals of the same race are reliably great enough for race to retain little utility as a biologic predictor. You might as well sort people by height. Or, in the words of an editorial writer for Nature Biotechnology in 2005, “Pooling people in race silos is akin to zoologists grouping raccoons, tigers and okapis on the basis that they are all stripy.”

But old misconceptions die hard, particularly for entrepreneurs eagerly awaiting cash bonanzas from the genomic revolution.

Race may be irrelevant; it may be, as Dr. Francis Collins, the director of the National Institutes of Health, put it, “a weak and imperfect proxy” for genetic differences. But it is also a familiar concept — and asking people what race they are is substantially cheaper than genotyping them.

So in a peculiar paradox, race has come to serve in some circles as a crude surrogate for genetic analysis until actual genomic medicine comes along — a temporary bridge from now to later, known to be flawed but still a quasi-legitimate stand-in for the real thing.

Against this background unfolds the story of BiDil, a drama of greed and good intentions.

Several observations prompted the drug’s development. Among them was the common assertion from the last century that blacks with heart failure were more likely to die than whites. (Mr. Kahn does an impressive job of researching and debunking this statistic.) Then there was the belief that blacks often reacted badly to some of the newer drugs used for treating heart failure, and the results of a study dating from the 1980s suggesting that many black patients did well with two old standby drugs.

Those two drugs were (and are) on sale as generics, costing pennies a pill. But just suppose they were combined into a single pill that could be then specifically marketed to patients who just happened to be thought in particular need of effective medication? Now there was a pharmacologic and marketing plan that would extend a lucrative new patent for decades.

And so it came to pass that a collection of eager investors and some of the nation’s foremost cardiologists smiled on the results of an industry-sponsored trial performed on self-identified black subjects with heart failure: The two cheap drugs combined into the not-so-cheap BiDil reduced mortality by 40 percent compared with placebo. This figure was impressive enough to end the trial early and speed BiDil to market.

How did whites do on BiDil? Nobody bothered to check.

Mr. Kahn deserves credit for teasing out all the daunting complexities behind these events, including the details of genetic analysis, the perils of racial determinations and the minutiae of patent law. Unfortunately, though, he suffocates his powerful subject in a dry, repetitive, ponderous read.

A law professor with a doctorate in history and longstanding interest in race issues, Mr. Kahn trudges a partisan path through the drama in which he himself was a player. (He testified before an F.D.A. advisory committee that BiDil should be approved without racial qualifications.)

He heads bravely into many statistical thickets, but omits relevant clinical data; he repeatedly refers to the trial that led to BiDil’s approval, for instance, but I could find its numerical findings nowhere in the book and had to look them up. In a story that fairly drips with potential human interest, he offers the reader not one sip.

The issues raised on every page are so important and so thought-provoking that it would be irresponsible to warn interested readers away. Still, it would be almost as irresponsible to misrepresent the difficulty of the journey.

As it happens, BiDil itself has had a remarkably inglorious career. Despite its much-trumpeted release, patients did not request the medication, and practicing doctors did not prescribe it.

NitroMed, the company that developed it, sponsored no further studies and failed in 2009.

The drug still lingers on the market; Mr. Kahn writes that BiDil may be resurrected in sustained-release form — that other time-honored technique for wringing a few more years from a drug’s patent.

For a parable of early 21st-century medicine, as it treads water between past and future and never hesitates to reach for a buck, it doesn’t get much better than BiDil.

Read More..

Books: From Bang to Whimper: A Heart Drug’s Story

On June 23, 2005, American medicine managed to take a small step forward and a giant step backward at precisely the same time, with government approval of the first medication to be earmarked for a specific racial group. It was BiDil, a drug designed to treat heart failure in blacks.

Enthusiasts hailed BiDil’s approval by the Food and Drug Administration as a landmark event in the nascent field of pharmacogenomics, which aims to create drugs tailored to fit an individual’s genetic makeup as precisely as a bespoke suit drapes its owner’s shoulders. Critics just winced and clocked one more misstep in medicine’s long history of race-related disasters.

You would think that the elucidation of the human genome would have cleared up most of the hoary untruths surrounding race and health. But as Jonathan Kahn makes clear in his worthy if convoluted review of the events surrounding the birth of BiDil, the genome has in many respects only made things worse.

It has been clear for decades that race has minimal relevance to the body’s inner workings. Research has repeatedly shown that the biologic variations among individuals of the same race are reliably great enough for race to retain little utility as a biologic predictor. You might as well sort people by height. Or, in the words of an editorial writer for Nature Biotechnology in 2005, “Pooling people in race silos is akin to zoologists grouping raccoons, tigers and okapis on the basis that they are all stripy.”

But old misconceptions die hard, particularly for entrepreneurs eagerly awaiting cash bonanzas from the genomic revolution.

Race may be irrelevant; it may be, as Dr. Francis Collins, the director of the National Institutes of Health, put it, “a weak and imperfect proxy” for genetic differences. But it is also a familiar concept — and asking people what race they are is substantially cheaper than genotyping them.

So in a peculiar paradox, race has come to serve in some circles as a crude surrogate for genetic analysis until actual genomic medicine comes along — a temporary bridge from now to later, known to be flawed but still a quasi-legitimate stand-in for the real thing.

Against this background unfolds the story of BiDil, a drama of greed and good intentions.

Several observations prompted the drug’s development. Among them was the common assertion from the last century that blacks with heart failure were more likely to die than whites. (Mr. Kahn does an impressive job of researching and debunking this statistic.) Then there was the belief that blacks often reacted badly to some of the newer drugs used for treating heart failure, and the results of a study dating from the 1980s suggesting that many black patients did well with two old standby drugs.

Those two drugs were (and are) on sale as generics, costing pennies a pill. But just suppose they were combined into a single pill that could be then specifically marketed to patients who just happened to be thought in particular need of effective medication? Now there was a pharmacologic and marketing plan that would extend a lucrative new patent for decades.

And so it came to pass that a collection of eager investors and some of the nation’s foremost cardiologists smiled on the results of an industry-sponsored trial performed on self-identified black subjects with heart failure: The two cheap drugs combined into the not-so-cheap BiDil reduced mortality by 40 percent compared with placebo. This figure was impressive enough to end the trial early and speed BiDil to market.

How did whites do on BiDil? Nobody bothered to check.

Mr. Kahn deserves credit for teasing out all the daunting complexities behind these events, including the details of genetic analysis, the perils of racial determinations and the minutiae of patent law. Unfortunately, though, he suffocates his powerful subject in a dry, repetitive, ponderous read.

A law professor with a doctorate in history and longstanding interest in race issues, Mr. Kahn trudges a partisan path through the drama in which he himself was a player. (He testified before an F.D.A. advisory committee that BiDil should be approved without racial qualifications.)

He heads bravely into many statistical thickets, but omits relevant clinical data; he repeatedly refers to the trial that led to BiDil’s approval, for instance, but I could find its numerical findings nowhere in the book and had to look them up. In a story that fairly drips with potential human interest, he offers the reader not one sip.

The issues raised on every page are so important and so thought-provoking that it would be irresponsible to warn interested readers away. Still, it would be almost as irresponsible to misrepresent the difficulty of the journey.

As it happens, BiDil itself has had a remarkably inglorious career. Despite its much-trumpeted release, patients did not request the medication, and practicing doctors did not prescribe it.

NitroMed, the company that developed it, sponsored no further studies and failed in 2009.

The drug still lingers on the market; Mr. Kahn writes that BiDil may be resurrected in sustained-release form — that other time-honored technique for wringing a few more years from a drug’s patent.

For a parable of early 21st-century medicine, as it treads water between past and future and never hesitates to reach for a buck, it doesn’t get much better than BiDil.

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